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KMID : 0985520120170020028
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Korean Journal of Pancreas and Biliary Tract
2012 Volume.17 No. 2 p.28 ~ p.32
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Estimating the Diagnostic Accuracy of Procalcitonin as a Marker for Post-ERCP Pancreatitis
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Kim Jong-Bum
Lee Bong-Kyu
Seo Young-Ho
Lee Nam-Hun
Lee Jung-Min
Bak Seung-Wook
An Hong-Ju
Lee Sang-Sun
Song Ho-Yeong
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Abstract
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Backgrounds/Aims: Pancreatitis is the most common complication of endoscopic retrograde cholangiopancreatography (ERCP). We wanted to evaluate serum procalcitonin as a marker for early prediction of post-ERCP pancreatitis.
Methods: Prospective single center study of 94 patients undergoing ERCP between November 2011 and July 2012 were performed. Blood samples for serum procalcitonin were obtained immediately, 4 hours, and 24 hours after ERCP. The definition of post-ERCP pancreatitis and the grade of its severity were based on consensus criteria
Result: The incidence of post-ERCP pancreatitis was 16.0% (15 patients). Thirteen had mild pancreatitis, 2 had moderate pancreatitis, and none had severe pancreatitis. The procalcitonin levels in post-ERCP pancreatitis group and no pancreatitis group were 0.28±0.38 vs. 0.47±0.58 ng/ml for immediately, 0.31±0.42 vs. 0.45±0.53 ng/ml for 4 hours and 0.28±0.39 vs. 0.46±0.46 ng/ml for 24 hours. The levels of serum procalcitonin were not significantly different between post-ERCP pancreatitis group and no pancreatitis group (p=0.129 for immediately, p=0.275 for 4 hours, and p=0.266 for 24 hours)
Conclusion: There was no significant difference in the level of serum procalcitonin level between post-ERCP pancreatitis and no pancreatitis group.
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KEYWORD
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procalcitonin, pancreatitis, endoscopic retrograde cholangiopancreatography (ERCP)
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